发明名称 |
CINNAMIC ACID HYDROXYAMIDES AS INHIBITORS OF HISTONE DEACETYLASE 8 |
摘要 |
<p>Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of histone deacetylase 8 (HDAC8). Also described herein are methods of using such HDAC8 inhibitors, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of HDAC8 activity.</p> |
申请公布号 |
EP2797875(A1) |
申请公布日期 |
2014.11.05 |
申请号 |
EP20120863933 |
申请日期 |
2012.12.19 |
申请人 |
PHARMACYCLICS, INC. |
发明人 |
VERNER, ERIK;CHEN, WEI;BALASUBRAMANIAN, SRIRAM |
分类号 |
C07C259/06;A61K31/165;A61P43/00;C07C311/08;C07D211/42;C07D211/46;C07D213/30;C07D213/36;C07D213/65;C07D213/68;C07D213/82;C07D213/89;C07D295/088;C07D401/06;C07D405/06 |
主分类号 |
C07C259/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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