| 摘要 |
Described is a method for preparing or modifying an array surface having a multiplicity of different polymeric species arranged thereon. The method comprises exposing the surface to a plasma or glow discharge so as to form or modify the properties of the multiplicity of polymeric species. The surface roughness can be modified by the plasma. The reactivity of groups on the surface of the polymeric species can also be modified to allow attachment of additional functionality. The plasma can also be used to effect the polymerisation of a monomer mixture in order to form the polymeric species, via plasma polymerisation. Exemplified is the use of plasma polymerisation on low vapour pressure amino acids to generate a peptide array. Also described are microarrays produced by the method. |
