| 发明名称 |
POLY (ADP-RIBOSE) POLYMERASE INHIBITOR |
| 摘要 |
Disclosed are a phthalic hydrazide (phthalazine ketone) compound, and a pharmaceutical composition comprising the same. As a DNA repair enzyme poly (ADP-ribozyme) polymerase inhibitor, the compound and the pharmaceutical composition can effectively treat diseases involving PARP enzymatic activity, including cancer, neural degenerative diseases, inflammation and the like. |
| 申请公布号 |
EP2799435(A1) |
申请公布日期 |
2014.11.05 |
| 申请号 |
EP20120852659 |
申请日期 |
2012.12.03 |
| 申请人 |
CHENGDU DI'AO PHARMACEUTICAL GROUP CO. LTD. |
发明人 |
JI, JIANXIN;GUO, NA;XUE, TING;KANG, BINGQIANG;YE, XINFA;CHEN, XIN;ZHANG, TAO |
| 分类号 |
C07D401/12;A61K31/502;A61K31/5025;A61P9/00;A61P35/00;C07D401/14;C07D407/14;C07D409/14;C07D413/14;C07D417/14 |
主分类号 |
C07D401/12 |
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