| 发明名称 |
NORMALIZATION OF CULTURE OF CORNEAL ENDOTHELIAL CELLS |
| 摘要 |
<p>The present invention provides a method for the normalized culturing ofcorneal endothelial cells. More specifically, the present invention provides a culture-normalizing-agent of a corneal endothelial cell, comprising a fibrosis inhibitor. In detail, the present invention provides a culture-normalizing agent comprising a transforming growth factor (TGF) ² signal inhibitor. The present invention also provides a culture medium for culturing a corneal endothelial cell normally, which comprises the culture-normalizing agent according to the present invention and corneal endothelium culture components. The present invention also provides a method for culturing a corneal endothelial cell normally, comprising the step of culturing a corneal endothelial cell using the culture-normalizing agent according to the present invention or the culture medium according to the present invention.</p> |
| 申请公布号 |
EP2799537(A1) |
申请公布日期 |
2014.11.05 |
| 申请号 |
EP20120862290 |
申请日期 |
2012.12.27 |
| 申请人 |
KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION;THE DOSHISHA;SENJU PHARMACEUTICAL CO., LTD. |
发明人 |
KINOSHITA, SHIGERU;KOIZUMI, NORIKO;OKUMURA, NAOKI |
| 分类号 |
C12N5/071;A61K9/70;A61K31/4418;A61K35/12;A61L27/00;A61P27/02;A61P43/00;C12N15/09 |
主分类号 |
C12N5/071 |
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