BLOOD DIAGNOSTIC KIT FOR DIAGNOSIS OF PROTEIN AGGREGATION AND MISFOLDING RELATED DISEASES OR DISORDERS USING THE DISSOCIATION OF PROTEIN AGGREGATES IN BODY

摘要

The present invention relates to a blood diagnostic kit using a dissociation process of protein aggregates in the body for the diagnosis of disorders or diseases related to abnormal protein aggregation or misfolding. The blood diagnostic kit measures the concentrations of beta-amyloid monomers in the plasma before and after administering a composition capable of monomerizing beta-amyloid. Accordingly, the blood diagnostic kit allows the accurate diagnosis of disorders or diseases related to abnormal protein aggregation or misfolding by concentration analysis using a dissociation process of aggregated protein which incurs diseases or disorders such as Alzheimer′s disease caused by beta-amyloid aggregation and the like and other diseases or disorders caused by protein aggregation. Therefore, the blood diagnostic kit can have the effects of drugs which prevent the accumulation of beta-amyloid and protein and increases the accuracy of analysis by monomerizing beta-amyloid and protein in the body to perform hematologic diagnosis.