Multiplexed nanoscale electrochemical sensors for multi-analyte detection

摘要

Provided are nanoscale devices suitable for multiplexed, parallel detection of multiple analytes and methods for fabricating such devices.

主权项

1. A sensing device, comprising:
a substrate having a longest dimension and having a plurality of tubular apertures formed therein; at least some of the apertures having an interior sidewall surface; the substrate being characterized as an elongated capillary having an exterior surface; at least some of the tubular apertures penetrating through the entirety of the substrate in the longest dimension of the substrate; at least one of the apertures having an electrode disposed within the aperture that conforms to at least part of the interior sidewall surface of the aperture; at least one of the electrodes being individually addressable at least a portion of the exterior surface of the capillary being characterized as undulating in shape and at least partially conforming to the interior sidewall surface shape of at least one of the apertures; and at least one electrode defining a lumen having a diameter in the range of from about 10 nm to about 100 micrometers.