Renal denervation and stimulation employing wireless vascular energy transfer arrangement

摘要

Devices, systems, and methods provide for intravascular or extravascular delivery of renal denervation therapy and/or renal control stimulation therapy. Wireless vascular thermal transfer apparatuses and methods provide for one or both of production of current densities sufficient to ablate renal nerves and terminate renal sympathetic nerve activity, and production of current densities sufficient to induce endothelium dependent vasodilation of the renal artery bed. A common apparatus may be used for both renal ablation and control of renal function locally after renal denervation.

主权项

1. An apparatus for intravascular delivery of a therapy to a first vessel of a patient, comprising:
a stent dimensioned for deployment within the first vessel, the stent adapted for chronic fixation within the first vessel; a controller supported by the stent; an electrode arrangement supported by the stent; an antenna arrangement supported by the stent and electrically coupled to the electrode arrangement, the antenna arrangement configured to receive energy from a power source external of the first vessel; the electrode and antenna arrangements operative in at least one of:
an ablation configuration that produces current densities sufficient to ablate target tissue at or proximate the vessel; anda stimulation configuration that produces current densities sufficient to induce endothelium dependent vasodilation of a first vessel bed; wherein the power source supplies energy to the antenna arrangement other than by way of a percutaneous electrical lead for at least the stimulation configuration.