发明名称 Allantoin-containing skin cream
摘要 An allantoin-containing skin cream composition can comprise allantoin and at least one anionic or nonionic emulsifier that is substantially hydrophilic and is soluble in water. The composition is in the form of an oil-in-water emulsion. The pH of the composition is in a range of from about 3.0 to about 6.0; preferably, the pH of the composition is from about 5.0 to about 6.0. The composition can further comprise an acidic anionic polymer. A preferred acidic anionic polymer is a carboxypolymethylene polymer. The composition can further comprise a carbohydrate polymer such as galactoarabinan, polygalactose or polyarabinose. The composition can additionally comprise other ingredients such as herbal extracts, an antioxidant component, an emollient component, a chelator, a solvent component, or a preservative component. The composition is useful as a skin protectant.
申请公布号 US8877790(B2) 申请公布日期 2014.11.04
申请号 US201314018167 申请日期 2013.09.04
申请人 Scioderm, Inc. 发明人 Farber Elliott
分类号 A61K31/4166;A61K8/02;A61K8/49;A61K8/46;A61K8/06;A61K47/20;A61K8/92;A61K9/00;A61Q17/04;A61Q17/00;A61K8/73;A61K8/37;A61K8/81;A61Q19/00;A61K8/86;A61K47/44;A61K8/97 主分类号 A61K31/4166
代理机构 Sterne, Kessler, Goldstein & Fox P.L.L.C. 代理人 Sterne, Kessler, Goldstein & Fox P.L.L.C.
主权项 1. A composition consisting essentially of an oil-in-water emulsion comprising: (a) allantoin; (b) an emulsifier system including beeswax and an anionic emulsifier that is substantially hydrophilic and is soluble in water; (c) an emollient component comprising one or more of lanolin oil, cetyl alcohol, stearyl alcohol, cod liver oil, and butylated hydroxytoluene; (d) an acid to adjust the pH of the composition to a value from about 4.5 to about 5.8; (e) water in an amount from about 50% to about 90% of the composition; (f) propylene glycol in an amount from about 2.0% to about 9.0% of the composition; (g) tetrasodium EDTA in an amount from about 0.05% to about 0.25% of the composition; (h) methylparaben in an amount from about 0.10% to about 0.50% of the composition; and (i) propylparaben in an amount from about 0.10% to about 0.50% of the composition, wherein the allantoin is stable in the composition for 30 days, 60 days, or 90 days at 40° C.
地址 Durham NC US