Lipid supplements for maintaining health and treatment of acute and chronic disorders

摘要

Nutritional supplement formulations suitable for specific enhancement of cell and mitochondrial function comprise enriched formulations of phospholipids and chemical precursors containing specifically identified concentrations of phosphatidylglycerol, phosphatidic acid and phosphatidylcholine, and mitochondrial and cell membrane phospholipid molecules as well as other desirable constituents. Methods of enriching extracted sources of cell and mitochondrial membrane molecules and precursors from microbes, plants and other sources are also set forth. The formulae can be combined with nutritional, prebiotic, and probiotic (microbial) factors that increase bioavailability through the digestive tract and increase absorption at the cellular and subcellular levels. These lipid combinations can be used to treat mitochondrial disorders associated with medical pathologies, chronic illnesses and syndromes, or to maintain lipid balance for normal mitochondrial function, and can be administered in many different forms. The various combinations specifically enriched in the correct phospholipid and correct fatty acid residues can be used to treat organ, tissue, cell or system.

主权项

1. A composition consisting of therapeutic components and a suitable carrier medium for delivery of said therapeutic components to an individual, said composition in the form of a tablet, capsule or powder for maintaining or restoring cell and mitochondrial health in the individual, or a specific organ system within that individual, or treating the individual having a specific disease or phospholipid deficiency, said therapeutic components consisting of a mixture of inulin and a phospholipid mixture consisting of phosphatidylglycerol and one or more phospholipids selected from the group consisting of phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylinositol (PI), and phosphatidylserine (PS), and one or more of linoleic acid (LA) and phosphatidic acid, wherein:
a) the phospholipids in said mixture, in combination with the inulin, are selected to maintain the phospholipids existing in the body of said individual at a predetermined proper phospholipid level to maintain mitochondrial health, or b) when delivered to said individual having a phospholipid deficiency, one or more of said phospholipids in said composition are selected to increase the quantity of said deficient phospholipids within said individual.