COMPOSTO, COMPOSTO OU SAL DO MESMO, COMPOSIÇÃO FARMACÊUTICA, MODULADOR DE RECEPTOR DE GLICOCORTICÓIDE, MÉTODO PARA PREVENÇÃO E/OU TRATAMENTO DE BISTÚRBIOS METABÓLICOS, DOENÇAS INFLAMATÓRIAS, DOENÇAS AUTO-IMUNES, DOENÇAS ALÉRGICAS, DOENÇAS DO SISTEMA NERVOSO CENTRAL, DOENÇAS CARDIOVASCULARES, DOENÇAS RELACIONADAS COM HOMEOSTASE OU GLAUCOMA, E USO DE PELO MENOS UM COMPOSTO OU UM SAL DO MESMO

摘要

The compounds represented in general formula (1) or a salt thereof are useful for glucocorticoid receptor modulators. In the formula, R 1 represents a lower alkyl group, a lower cycloalkyl group, an aryl group and the like; R 2 represents a hydrogen atom, a lower alkyl group and the like; R 3 represents a hydrogen atom, a lower alkyl group and the like; R 4 and R 5 represent a hydrogen atom, a lower alkyl group and the like; R 6 represents a hydrogen atom, a lower alkyl group and the like; R 7 represents a hydrogen atom, a lower alkyl group, a lower alkenyl group and the like; W represents an oxygen atom, a sulfur atom, NR 8 and the like; R 8 represents a hydrogen atom, a lower alkyl group and the like; X represents an oxygen atom or a sulfur atom; Y represents a lower alkylene group and the like; Z represents an oxygen atom, a sulfur atom, NR 9 , OCO or OSO 2 ; R 9 represents a hydrogen atom, a lower alkyl group and the like respectively.