Method of producing aloe vera extract

摘要

The present invention provides: an Aloe vera extract that can be safely ingested, can be used as a material of food for preventing lifestyle diseases, contains an extremely low level of an anthraquinone (anthraquinone-based compound), and can be added to foods; and a method of producing the Aloe vera extract. A supercritical fluid extraction method can produce an Aloe vera extract containing a mixture that consists of a cyclolanostane compound and a lophenol compound in an amount of 1.0% by mass or more and having the following properties (1) and/or (2):
(1) the mass mixing ratio of the cyclolanostane compound and lophenol compound is as follows:
cyclolanostane compound:lophenol compound=6.3:2.7 to 5.1:4.9; and/or(2) the content of an anthraquinone-based compound is 0.001% by mass or less.

主权项

1. A method of making a supercritical fluid extract of Aloe vera for treating hyperglycemia, wherein
the method comprises the following (a) and (b):
(a) preparing powdery Aloe vera mesophyll, wherein said mesophyll part excludes leaf skin of Aloe vera, by removing water from the mesophyll part of Aloe vera by freeze-drying or hot-air drying to provide a powdery Aloe vera mesophyll; and(b) extracting the powdery Aloe vera mesophyll by supercritical fluid extraction with an extraction solvent, wherein said extraction solvent is carbon dioxide, at an extraction temperature within a range of 50 to 69° C., at a pressure within a range of 15 to 24 MPa, at an extraction time within a range of 50 to 70 minutes, and without using an entrainer to provide the super critical fluid extract of Aloe vera, wherein the supercritical fluid extract of Aloe vera comprises a mixture that consists of a cyclolanostane compound and a lophenol compound in an amount of 1.0% by mass or more, and wherein supercritical fluid extract of Aloe vera contains one or more anthroquinone compounds in an amount of 0.001% or less.