Phospholipid ether analogs as agents for detecting and locating cancer, and methods thereof

摘要

The present invention provides methods for treating, detecting and locating recurrence of cancer, radiation and chemo insensitive cancer or metastasis of cancer selected from the group consisting of Lung cancer, Adrenal cancer, Melanoma, Colon cancer, Colorectal cancer, Ovarian cancer, Prostate cancer, Liver cancer, Subcutaneous cancer, Squamous cell cancer, Intestinal cancer, Hepatocellular carcinoma, Retinoblastoma, Cervical cancer, Glioma, Breast cancer and Pancreatic cancer in subject using phospholipid ether analogs.

主权项

1. A method for detecting cancer in vivo, the method comprising:
administering 124I labeled 18-(p-iodophenyl)octadecyl phosphocholine to a subject; and determining whether an organ suspected of having cancer in the subject retains a higher level of the 124I-labeled 18-(p-iodophenyl)octadecyl phosphocholine than surrounding regions, wherein a higher retention level of 124I-labeled 18-(p-iodophenyl)octadecyl phosphocholine indicates cancer.