发明名称 |
Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors |
摘要 |
A compound of formula (I):;
wherein:
M is hydrogen or a pharmaceutically acceptable salt-forming cation;and R1 and M are as defined herein. Also, methods of treating bacterial infection, pharmaceutical compositions, molecular complexes and processes for preparing compounds. |
申请公布号 |
US8877743(B2) |
申请公布日期 |
2014.11.04 |
申请号 |
US201313917932 |
申请日期 |
2013.06.14 |
申请人 |
Naeja Pharmaceutical Inc. |
发明人 |
Maiti Samarendra N.;Nguyen Dai;Khan Jehangir;Ling Rong |
分类号 |
A61K31/439;A61K31/5377;A61K31/4985;A61K45/06;A61K31/553;A61K31/55;A61K31/541;A61K31/496;C07D471/08;C07D519/00;A61K31/46;C07D451/06 |
主分类号 |
A61K31/439 |
代理机构 |
Roylance, Abrams, Berdo & Goodman, L.L.P. |
代理人 |
Roylance, Abrams, Berdo & Goodman, L.L.P. |
主权项 |
1. A compound of formula (I): wherein: M is hydrogen or a pharmaceutically acceptable salt-forming cation; R1 is a radical selected from the group consisting of:
(1) C1-6 straight or branched chain alkyl which is optionally substituted; and(2) C3-7 cycloalkyl which is optionally substituted; or a deuterated compound of any such compound. |
地址 |
Edmonton, AB CA |