发明名称 Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors
摘要 A compound of formula (I):; wherein: M is hydrogen or a pharmaceutically acceptable salt-forming cation;and R1 and M are as defined herein. Also, methods of treating bacterial infection, pharmaceutical compositions, molecular complexes and processes for preparing compounds.
申请公布号 US8877743(B2) 申请公布日期 2014.11.04
申请号 US201313917932 申请日期 2013.06.14
申请人 Naeja Pharmaceutical Inc. 发明人 Maiti Samarendra N.;Nguyen Dai;Khan Jehangir;Ling Rong
分类号 A61K31/439;A61K31/5377;A61K31/4985;A61K45/06;A61K31/553;A61K31/55;A61K31/541;A61K31/496;C07D471/08;C07D519/00;A61K31/46;C07D451/06 主分类号 A61K31/439
代理机构 Roylance, Abrams, Berdo & Goodman, L.L.P. 代理人 Roylance, Abrams, Berdo & Goodman, L.L.P.
主权项 1. A compound of formula (I): wherein: M is hydrogen or a pharmaceutically acceptable salt-forming cation; R1 is a radical selected from the group consisting of: (1) C1-6 straight or branched chain alkyl which is optionally substituted; and(2) C3-7 cycloalkyl which is optionally substituted; or a deuterated compound of any such compound.
地址 Edmonton, AB CA