Continuous flow synthesis of amino alcohols using microreactors

摘要

The present invention provides various methods for the synthesis of chemical species in a microreactor environment. In some cases, reaction products of the present invention may be valuable as intermediates and/or products in pharmaceutical and polymer research. For example, the method may involve the synthesis of amino alcohols within a microchannel. Embodiment described herein may allow for reactions with significantly shorter reaction times and increased efficiency.

主权项

1. A method for synthesizing an amino alcohol, comprising:
providing a continuous flow microreactor comprising a microchannel, a first inlet in fluid communication with a source of an epoxide species and the microchannel, and a second inlet in fluid communication with a source of an amine species and the microchannel; flowing a fluid sample comprising the epoxide species and the amine species into the microchannel; and reacting, in the microchannel, the epoxide species and the amine species to form an amino alcohol.