| 摘要 |
<p>The invention relates to anti-α2 integrin antibodies and their uses. Humanized antibodies are disclosed that bind to the I domain ofα2 integrin and inhibit the interaction ofα2β1 integrin with collagen. Also disclosed are therapeutic uses of anti-α2 integrin antibodies in treatingα2β1-mediated disorders, including anti-α2 integrin antibodies that bind toα2 integrin without activating platelets.</p> |
