| 摘要 |
Discloses a binding protein comprising first and second polypeptide chains, each independently comprising VD-(X1)n-VD2-C-(X2)n, wherein the VD1 and VD2 domains form functional binding sites, wherein the functional binding sites bind to IL-1B and are comprised of the following CDR sequences. CDR H1 - RYDMS CDR H2 - YISHGGAGTYYPDSVK CDR H3 - YFDVWGQG CDR L1 - RASGNIHNYLT CDR L2 - NAKTLA CDR L3 - QHFWSIPY |
