摘要 |
The invention relates to an improved method of preparing oxymorphone or a salt thereof from oripavine. In particular, the invention relates to a method of preparing oxymorphone with a content of alpha-beta- unsaturated ketones (ABUK) < 10 ppm, wherein the content of 8,14-dihydroxydihydromorphinone in the prepared oxymorphone is > 10 ppm. |