IMPLANTABLE DEVICE WITH PLASMA POLYMER SURFACE

摘要

A deformable implantable medical device such as a stent comprising metallic, polymer and/or composite substrate having a columnar structured plasma polymer surface capable of binding functional biological molecules. The polymer surface can be bound to the substrate through a mixed or graded interface formed by a co-deposition process where a substrate material is deposited with carbon containing species while gradually reducing the substrate material proportion and increasing the carbon containing species proportion. The device is able to undergo deformation without substantial delamination of the plasma polymer surface.

主权项

1. A deformable implant comprising a metallic substrate, the substrate being bound through a mixed or graded interface to a columnar structured and hydrophilic plasma polymer surface that is activated to enable direct covalent binding to a functional biological molecule, the plasma polymer surface comprising a sub-surface that includes a plurality of cross-linked regions, wherein the implant is a stent that is able to undergo deformation without substantial delamination of the plasma polymer surface.