发明名称 COMBINATION
摘要 The present invention relates to a method of treating cancer in a human and to pharmaceutical combinations useful in such treatment. In particular, the method relates to a cancer treatment method that includes administering 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide, or a pharmaceutically acceptable salt thereof, and N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)6,8-dimethy;-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide, or a pharmaceutically acceptable salt or solvate thereof, to a human in need thereof.
申请公布号 US2014323506(A1) 申请公布日期 2014.10.30
申请号 US201414327660 申请日期 2014.07.10
申请人 GlaxoSmithKline Intellectual Property Development Limited 发明人 GILMER Tona M.;KUMAR Rakesh;Liu Li
分类号 A61K31/519;A61K31/506 主分类号 A61K31/519
代理机构 代理人
主权项 1. A combination comprising: (i) a compound of Structure (I): or a pharmaceutically acceptable salt thereof; and (ii) a compound of Structure (II): or a pharmaceutically acceptable salt or solvate thereof.
地址 Brentford GB