发明名称 Uses Of Peptides to Treat Brain Injury and Disease
摘要 A method of treating loss of brain function in a patient comprising the steps of preparing a composition comprising a D peptide and a pharmaceutically acceptable carrier. The D peptide has the general structure: A-B-C-D-E-F-G-H in which A is Ala, or absent,B is Ser, Thr or absent,C is Ser, Thr or absent,D is Ser, Thr, Asn, Glu, Arg, Ile, Leu,E is Ser, Thr, Asp, Asn,F is Thr, Ser, Asn, Arg, Gln, Lys, Trp,G is Tyr, andH is Thr, Ser, Arg, Gly. All amino acids in the D peptide are the D stereoisomeric configuration. The peptide composition is administered in a therapeutically effective dose.
申请公布号 US2014323393(A1) 申请公布日期 2014.10.30
申请号 US201414263347 申请日期 2014.04.28
申请人 Ruff Michael 发明人 Ruff Michael
分类号 C07K7/06 主分类号 C07K7/06
代理机构 代理人
主权项 1. A method of treating loss of brain function in a patient comprising the steps of: preparing a composition comprising a D peptide and a pharmaceutically acceptable carrier, said D peptide further comprises the general structure: A-B-C-D-E-F-G-H in which: A is Ala, or absent, B is Ser, Thr or absent, C is Ser, Thr or absent, D is Ser, Thr, Asn, Glu, Arg, Ile, Leu, E is Ser, Thr, Asp, Asn, F is Thr, Ser, Asn, Arg, Gln, Lys, Trp, G is Tyr, and H is Thr, Ser, Arg, Gly, and wherein all amino acids are the D stereoisomeric configuration, and administering said composition to the patient in a therapeutically effective dose, wherein said composition acts to treat the loss of brain function in the patient.
地址 Potomac MD US