| 发明名称 |
TARGETING MICRORNAS MIR-409-5P, MIR-379 AND MIR-154* TO TREAT PROSTATE CANCER BONE METASTASIS AND DRUG RESISTANT LUNG CANCER |
| 摘要 |
The present invention describes methods of treating cancer, cancer metastasis, and drug resistant cancers using miRNA inhibitors; for example, inhibitors of miR-409-5p. Also described are methods of using the miRNA as biomarkers; for example, to predict responsiveness to a cancer drug, to detect a disease state of cancer. |
| 申请公布号 |
US2014323551(A1) |
申请公布日期 |
2014.10.30 |
| 申请号 |
US201214360489 |
申请日期 |
2012.11.30 |
| 申请人 |
Cedars-Sinal Medical Center |
发明人 |
Chung Leland W.K.;Josson Sajni;Gururajan Murali;Jain Anjali |
| 分类号 |
C12N15/113;C12Q1/68;G01N33/50 |
主分类号 |
C12N15/113 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method, comprising:
providing a miRNA inhibitor; and administering the miRNA inhibitor to a subject in need of treatment for cancer, in need of treatment for cancer metastasis, or in need of lowering or treatment for cancer drug resistance to treat cancer, to treat cancer metastasis, or to lower or treat cancer drug resistance. |
| 地址 |
Los Angeles CA US |
