发明名称 DO3A-DIAMINOBIPHENYL COMPOUNDS AND GADOLINIUM COMPLEX COMPRISING THE SAME COMPOUNDS AS A LIGAND
摘要 <p>The present invention relates to a DO3A-diaminobiphenyl compound and a gadolinium complex comprising the DO3A-diaminobiphenyl compound as a ligand, and, more specifically, to a DO3A-diaminobiphenyl compound, a gadolinium complex comprising the DO3A-diaminobiphenyl compound as a ligand, an MRI contrast agent comprising the gadolinium complex, and a preparing method thereof. According to the present invention, the compound formed by a DO3A structure and a biphenyl structure, which are combined together, forms the gadolinium complex together with gadolinium so as to show an effect of contrast enhancement and blood pool enhancement.</p>
申请公布号 KR20140125896(A) 申请公布日期 2014.10.30
申请号 KR20130042628 申请日期 2013.04.18
申请人 KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION 发明人 KIM, TAE JEONG;CHANG, YONG MIN
分类号 C07D403/12;A61K49/06;C07D257/02;C07F5/00 主分类号 C07D403/12
代理机构 代理人
主权项
地址