发明名称 |
METHODS AND COMPOSITION RELATED TO BROWN ADIPOSE-LIKE CELLS |
摘要 |
<p>Methods and therapeutics are provided for treating diseases, including metabolic diseases and other weight-related disorders. Generally, methods for making brown adipose-like including culturing a population of artery-derived cells in adipogenic induction medium for a period of time and under conditions sufficient to increase expression of at least one adipocyte marker at a higher level as compared to untreated artery-derived cells are disclosed. Isolated artery-derived, ex vivo differentiated brown adipose-like cells are also provided, including pharmaceutical compositions and cell delivery systems thereof. In another embodiment, a method of treating a subject is disclosed that includes obtaining a population of artery-derived brown adipose-like cells and administering the brown adipose-like cells into a target region in the subject.</p> |
申请公布号 |
SG11201404763X(A) |
申请公布日期 |
2014.10.30 |
申请号 |
SGX11201404763 |
申请日期 |
2013.02.14 |
申请人 |
DEPUY SYNTHES PRODUCTS, LLC |
发明人 |
SEYDA, AGNIESZKA;COLTER, DAVID C.;BUENSUCESO, CHARITO S.;KAZANECKI, CHRISTIAN C.;DHANARAJ, SRIDEVI |
分类号 |
C12N5/077 |
主分类号 |
C12N5/077 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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