| 发明名称 |
COMBINATION OF ANTI-CTLA4 ANTIBODY WITH TUBULIN MODULATING AGENTS FOR THE TREATMENT OF PROLIFERATIVE DISEASES |
| 摘要 |
Compositions and methods are disclosed which are useful of the treatment and prevention of proliferative disorders. |
| 申请公布号 |
US2014323533(A1) |
申请公布日期 |
2014.10.30 |
| 申请号 |
US201313872901 |
申请日期 |
2013.04.29 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
Jure-Kunkel Maria |
| 分类号 |
A61K31/426;A61K45/06;C07D493/04;C07D491/044 |
主分类号 |
A61K31/426 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for the treatment of proliferative diseases, including cancer, which comprises administering to a mammal in need thereof a synergistically, therapeutically effective amount of (1) at least one anti-CTLA-4 agent(s) and 2) a compound of formula I: |
| 地址 |
Princeton NJ US |
