| 发明名称 |
CALCIPOTRIOL MONOHYDRATE NANOCRYSTALS |
| 摘要 |
Calcipotriol monohydrate nanocrystals prepared by the process disclosed herein may be incorporated in a pharmaceutical composition for use in the prevention or treatment of dermal diseases and conditions. |
| 申请公布号 |
US2014322331(A1) |
申请公布日期 |
2014.10.30 |
| 申请号 |
US201414220843 |
申请日期 |
2014.03.20 |
| 申请人 |
LEO PHARMA A/S |
发明人 |
PETERSSON Karsten |
| 分类号 |
A61K31/592;A61K45/06;A61K9/06;C07C35/21 |
主分类号 |
A61K31/592 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A suspension of calcipotriol monohydrate in the form of nanocrystals of a particle size distribution in the range of 200-600 nm as determined by dynamic light scattering, the suspension further comprising an aqueous phase including a non-ionic, polymeric surfactant in an amount sufficient to prevent formation of aggregates and/or crystal growth of the calcipotriol monohydrate nanocrystals. |
| 地址 |
Ballerup DK |
