The present invention is directed to 2-hydroxymethyl compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
申请公布号
WO2014176144(A1)
申请公布日期
2014.10.30
申请号
WO2014US34748
申请日期
2014.04.21
申请人
MERCK SHARP & DOHME CORP.;KUDUK, SCOTT, D.;SKUDLAREK, JASON, W.