Controlled Release of Active Using pH

摘要

Dissolvable polymeric compositions are described which when exposed to certain pH conditions, controllably release one or more actives. The active agents can be nearly any active agent such as chlorhexidine gluconate (CHG). Also described are products using such compositions such as dressings. In addition, methods of controllably releasing one or more actives are described.

主权项

1. A polymeric composition adapted to controllably release at least one active agent, the composition comprising:
at least one polymer forming a polymeric matrix; at least one active agent dispersed in the polymeric matrix; wherein upon exposure to a pH of at least 6.5, the polymeric matrix dissolves thereby controllably releasing the at least one active agent from the composition.