发明名称 |
AXL ANTIBODY-DRUG CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER |
摘要 |
The present invention relates to an antibody-drug conjugate capable of binding to the protein Axl. From one aspect, the invention relates to an antibody-drug conjugate comprising an antibody capable of binding to Axl, said antibody being conjugated to at least one drug which is a pyrrolobenzodiazepme dimer (PBD dimer) drug. The invention also comprises method of treatment and the use of said antibody-drug conjugate for the treatment of cancer. |
申请公布号 |
WO2014174111(A1) |
申请公布日期 |
2014.10.30 |
申请号 |
WO2014EP58560 |
申请日期 |
2014.04.28 |
申请人 |
PIERRE FABRE MEDICAMENT;SPIROGEN SARL |
发明人 |
BEAU-LARVOR, CHARLOTTE;GOETSCH, LILIANE;HOWARD, PHILIP WILSON |
分类号 |
A61K47/48 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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