| 发明名称 |
METHOD OF INDUCING NEUTRALIZING ANTIBODIES TO HUMAN IMMUNODEFICIENCY VIRUS |
| 摘要 |
The present invention relates, in general, to human immunodeficiency virus (HIV), and, in particular, to a method of inducing neutralizing antibodies to HIV and to compounds and compositions suitable for use in such a method. |
| 申请公布号 |
US2014322262(A1) |
申请公布日期 |
2014.10.30 |
| 申请号 |
US201214110490 |
申请日期 |
2012.04.09 |
| 申请人 |
Spicer Leonard D.;Reardon Patrick N.;Haynes Barton F.;Alam S. Munir |
发明人 |
Spicer Leonard D.;Reardon Patrick N.;Haynes Barton F.;Alam S. Munir |
| 分类号 |
A61K39/385;A61K39/21 |
主分类号 |
A61K39/385 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An immunogenic conjugate comprising a trimerization domain N-terminal to an HIV-1 Env membrane proximal external region (MPER) peptide, wherein said MPER peptide is present as a trimer attached to a biological membrane mimetic. |
| 地址 |
Durham NC US |
