INFLUENZA VACCINES CONTAINING HEMAGGLUTININ AND MATRIX PROTEINS

摘要

PROBLEM TO BE SOLVED: To provide influenza vaccines containing hemagglutinin and matrix proteins.SOLUTION: An immunogenic composition comprising influenza virus haemagglutinin and matrix proteins is provided. These may be from influenza viruses grown in cell culture rather than eggs. The matrix protein may be a fragment of a full-length viral matrix protein e.g. a matrix M1 fragment with a molecular weight of less than 20kDa. The composition may be a subunit vaccine comprising purified surface glycoproteins.