摘要 |
<p>A method or monitoring and/or controlling a brain state of a subject includes acquiring physiological data from sensors including electrophysiological sensors and optical sensors, assembling, using data from the electrophysiological sensors, a time-series signal indicative of a brain activity of the subject, and identifying, using the time-series signal, a burst suppression state described by a burst suppression period and a burst period. The method also includes computing, using data from the optical sensors, parameters associated with the burst suppression state, the parameters indicative of least one of a metabolic process and a hemodynamic process, and estimating, using the parameters, time-series signal, and burst period, a response function describing a time course of the parameters correlated with a burst during the burst suppression period. The method further includes controlling a treatment using the response function to generate a target burst suppression state.</p> |
申请人 |
THE GENERAL HOSPITAL CORPORATION;PURDON, PATRICK, L.;BROWN, EMERY, N.;CHING, SHINUNG;BOAS, DAVID, A.;FRANCESCHINI, MARIA, ANGELA;SUTIN, JASON |
发明人 |
PURDON, PATRICK, L.;BROWN, EMERY, N.;CHING, SHINUNG;BOAS, DAVID, A.;FRANCESCHINI, MARIA, ANGELA;SUTIN, JASON |