发明名称 |
NOVEL VACCINES AGAINST APICOMPLEXAN PATHOGENS |
摘要 |
The technology provided herein generally relates to novel fusion proteins suitable as human and/or animal vaccines against parasites or pathogens of the phylum Apicomplexa. In particular, the present disclosure relates to novel fusion proteins as a basis for vaccines against Plasmodium parasites, including P. falciparum, P. vivax, P. malariae, P. ovale and P. knowlesi. Nucleic acid molecules encoding said fusion proteins, vectors, host cells containing the nucleic acids and methods for preparation and producing such fusion proteins; antibodies induced or generated by the use of said fusion proteins or said nucleic acid molecules encoding said fusion proteins and the use of such antibodies or recombinant derivatives for passive immunotherapy; methods for producing such fusion proteins; compositions and methods for using such fusion proteins for the prevention and treatment of malaria are also encompassed by the present disclosure. |
申请公布号 |
CA2910322(A1) |
申请公布日期 |
2014.10.30 |
申请号 |
CA20142910322 |
申请日期 |
2014.04.24 |
申请人 |
FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. |
发明人 |
BOES, ALEXANDER;SPIEGEL, HOLGER;GUVEN, EDGU;BEISS, VERONIQUE;SACK, MARKUS;REIMANN, ANDREAS;FISCHER, RAINER |
分类号 |
A61K39/002;A61K39/015;C12N15/62 |
主分类号 |
A61K39/002 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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