Method for determining hepatotoxicity of a compound.
摘要
The invention is in the field of molecular diagnostics. More in particular it provides marker genes for determining the hepatotoxicity of compounds. A method according to the invention employs samples obtained from zebrafish embryos exposed to a potentially hepatotoxic compound and determines expression levels of a number of marker genes in order to distinguish between hepatotoxic compounds and non-hepatotoxic compounds.
申请公布号
EP2796564(A1)
申请公布日期
2014.10.29
申请号
EP20130165649
申请日期
2013.04.26
申请人
RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU
发明人
VEN, VAN DER, LEONARDUS THEODORUS MARIA;DRIESSEN, MARJA