モルヒネ−６−グルクロニドの誘導体、これらの調製方法および治療におけるこれらの使用

摘要

The disclosure relates to derivatives of morphine-6-glucuronide of formula (I) wherein R1 is as defined in the disclosure, or an acid addition salt thereof, as well as in hydrate or solvate form. The disclosure also relates to the preparation method thereof and to the use of same in therapeutics.