| 摘要 |
Computer analysis of data sets representing images such as MRI images to achieve bias correction and image registration, each image including a bias in intensity within the image of unknown magnitude, is performed by: a) inputting a digital data set of a first image and a digital data set of a second image into a computer; b) calculating a deformation of said first image that transforms said first image into a transformed image that is an optimised approximation of said second image and c) simultaneously calculating and applying a bias correction which is applied to said first image and a bias correction which is applied to said transformed image such that each of the first image and the transformed image is individually corrected for bias therein. Generally, an average of the bias correction over the first image is equal and opposite to an average of the bias correction over said transformed image. |
