MULTIVALENT VACCINES FOR RABIES VIRUS AND FILOVIRUSES
摘要
<p>The present invention provides methods and compositions for inducing an immune response that confers dual protection against infections by either or both of a rabies virus and a filovirus, and/or which can be used therapeutically for an existing infection with rabies virus and/or a filovirus to treat at least one symptom thereof and/or to neutralize or clear the infecting agents. In particular, the present invention provides a recombinant rabies virus vector omprising a nucleotide sequence encoding at least one filovirus glycoprotein or an immunogenic fragment thereof, as well as pharmaceutical compostions comprising the vaccine vectors.</p>
申请公布号
EP2670843(B1)
申请公布日期
2014.10.29
申请号
EP20120702953
申请日期
2012.02.02
申请人
THE GOVERNMENT OF THE U.S.A, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES