发明名称 |
TARTRATE SALTS OR COMPLEXES OF QUINAZOLINE BASED EGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY |
摘要 |
<p>The present invention relates to tartrate salts of quinazoline containing zinc-binding moiety based derivatives of Formula II, below. These compounds are inhibitors of epidermal growth factor receptor tyrosine kinase (EGFR-TK) and may further act as HDAC inhibitors. The invention further relates to the use of these tartrate salts in the treatment of EGFR-TK related diseases and disorders such as cancer.</p> |
申请公布号 |
EP2190287(B1) |
申请公布日期 |
2014.10.29 |
申请号 |
EP20080743752 |
申请日期 |
2008.03.10 |
申请人 |
CURIS, INC. |
发明人 |
CAI, XIONG;QIAN, CHANGGENG;ZHAI, HAIXIAO |
分类号 |
C07D239/94;A61K31/517;A61P35/00 |
主分类号 |
C07D239/94 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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