发明名称 |
Medicated patch |
摘要 |
Provided is a medicated patch containing a medicinal agent, an adhesive base material and a tackifier, where the medicinal agent is varenicline or a pharmaceutically acceptable salt thereof, the adhesive base material is a rubbery adhesive base material and the tackifier is a rosin-based tackifier selected from the group consisting of rosin, rosin derivatives and hydrogenated products of the foregoing, or a non-rosin-based tackifier selected from the group consisting of aliphatic hydrocarbon resins and alicyclic hydrocarbon resins, and when a non-rosin-based tackifier is added as the tackifier, a solubilizer for the medicinal agent is further added, the solubilizer containing an alcohol-based solubilizer having at least a solubility parameter of 20-35. |
申请公布号 |
US8871249(B2) |
申请公布日期 |
2014.10.28 |
申请号 |
US200912919715 |
申请日期 |
2009.02.09 |
申请人 |
Hisamitso Pharmaceutical Co., Inc. |
发明人 |
Yamamoto Naoki;Morimoto Kumi;Takeuchi Akio;Ishigaki Kenji |
分类号 |
A61F13/00;A61K31/4985;A61K9/70 |
主分类号 |
A61F13/00 |
代理机构 |
Nath, Goldberg & Meyer |
代理人 |
Nath, Goldberg & Meyer ;Goldberg Joshua B.;Blackman Scott H. |
主权项 |
1. A medicated patch composition comprising a medicinal agent, an adhesive base material, a tackifier and a solubilizer for the medicinal agent,
wherein the medicinal agent is varenicline or a pharmaceutically acceptable salt thereof, the adhesive base material is a rubbery adhesive base material, the tackifier is a non-rosin-based tackifier selected from the group consisting of aliphatic hydrocarbon resins and alicyclic hydrocarbon resins, and the solubilizer is an alcohol-based solubilizer having a solubility parameter of 20-35. |
地址 |
Tosu-shi, Saga JP |