发明名称 Medicated patch
摘要 Provided is a medicated patch containing a medicinal agent, an adhesive base material and a tackifier, where the medicinal agent is varenicline or a pharmaceutically acceptable salt thereof, the adhesive base material is a rubbery adhesive base material and the tackifier is a rosin-based tackifier selected from the group consisting of rosin, rosin derivatives and hydrogenated products of the foregoing, or a non-rosin-based tackifier selected from the group consisting of aliphatic hydrocarbon resins and alicyclic hydrocarbon resins, and when a non-rosin-based tackifier is added as the tackifier, a solubilizer for the medicinal agent is further added, the solubilizer containing an alcohol-based solubilizer having at least a solubility parameter of 20-35.
申请公布号 US8871249(B2) 申请公布日期 2014.10.28
申请号 US200912919715 申请日期 2009.02.09
申请人 Hisamitso Pharmaceutical Co., Inc. 发明人 Yamamoto Naoki;Morimoto Kumi;Takeuchi Akio;Ishigaki Kenji
分类号 A61F13/00;A61K31/4985;A61K9/70 主分类号 A61F13/00
代理机构 Nath, Goldberg & Meyer 代理人 Nath, Goldberg & Meyer ;Goldberg Joshua B.;Blackman Scott H.
主权项 1. A medicated patch composition comprising a medicinal agent, an adhesive base material, a tackifier and a solubilizer for the medicinal agent, wherein the medicinal agent is varenicline or a pharmaceutically acceptable salt thereof, the adhesive base material is a rubbery adhesive base material, the tackifier is a non-rosin-based tackifier selected from the group consisting of aliphatic hydrocarbon resins and alicyclic hydrocarbon resins, and the solubilizer is an alcohol-based solubilizer having a solubility parameter of 20-35.
地址 Tosu-shi, Saga JP