| 发明名称 | Transglutaminase inhibitors and methods of use thereof | ||
| 摘要 | Transglutaminase inhibitors and methods of use thereof are provided. | ||
| 申请公布号 | US8871718(B2) | 申请公布日期 | 2014.10.28 |
| 申请号 | US201213693804 | 申请日期 | 2012.12.04 |
| 申请人 | The Board of Trustees of the Leland Stanford Junior University | 发明人 | Khosla Chaitan;Watts Richard Edward;Siegel Matthew John;Choi Kihang |
| 分类号 | A61K38/00;A61K31/4709;C07D413/14;C07K7/06;A61K45/06;C07D413/12;A61K31/42;C07D261/04;A61K31/421 | 主分类号 | A61K38/00 |
| 代理机构 | Bozicevic, Field & Francis LLP | 代理人 | Bozicevic, Field & Francis LLP ;Sherwood Pamela J. |
| 主权项 | 1. A pharmaceutical formulation comprising: an effective dose of a tTGase inhibitor of the formula: wherein R1 is quinolin-3-ylmethyl ester and R2 is a substituted or unsubstituted heterocyclyl or heterocyclylalkyl group; R3 is Br; n is 0; and X is NH. | ||
| 地址 | Palo Alto CA US | ||