System and method for monitoring diastolic function using an implantable medical device

摘要

Diastolic function is monitored within a patient using a pacemaker or other implantable medical device. In one example, the implantable device uses morphological parameters derived from the T-wave evoked response waveform as proxies for ventricular relaxation rate and ventricular compliance. In particular, the magnitude of the peak of the T-wave evoked response is employed as a proxy for ventricular compliance. The maximum slew rate of the T-wave evoked response following its peak is employed as a proxy for ventricular relaxation. A metric is derived from these proxy values to represent diastolic function. The metric is tracked over time to evaluate changes in diastolic function. In other examples, specific values for ventricular compliance and ventricular relaxation are derived for the patient based on the T-wave evoked response parameters.

主权项

1. A method for use with an implantable medical device for implant within a patient, the method comprising:
detecting a T-wave evoked response (ER) slew rate within the patient; estimating a ventricular relaxation rate of the patient from the T-wave ER slew rate; and controlling at least one device function based on the ventricular relaxation rate.