Therapeutic regimen comprising PEG-interferon, ribavirin and VX-950 for the treatment of hepatitis

摘要

The present invention relates to antiviral therapies and compositions for treating or preventing Hepatitis C infections in patients and relates to other methods disclosed herein. The invention also relates to kits and pharmaceutical packs comprising compositions and dosage forms.

主权项

1. A therapeutic regimen comprising administering to a patient infected with the hepatitis C virus peginterferon and ribavirin with VX-950 in an initial phase and administering peginterferon and ribavirin over a secondary phase, wherein the secondary phase occurs after the initial phase, and wherein the VX-950 administered in the initial phase is in an amount of 1125 mg twice per day, the peginterferon administered in the initial phase and in the secondary phase is in an amount of 180 micrograms per week and the ribavirin administered in the initial phase and in the secondary phase is in an amount of 1000 to 1200 mg per day.