Monitoring variation patterns in physiological parameters associated with myocardial instability

摘要

A method of analyzing myocardial instability includes obtaining a physiological parameter representative of myocardial behavior over a set of cardiac cycles and determining reversal points in the physiological parameter over the set of cardiac cycles. The method also includes identifying myocardial instability based on the reversal points in the physiological parameter. A reversal point may correspond to a value of the physiological parameter, during a current cardiac cycle, that exceeds or is less than the values of the physiological parameter during prior and subsequent cardiac cycles. Optionally, the method includes calculating differences between values of the physiological parameter for consecutive cardiac cycles and detecting the reversal points when a current difference exceeds or is less than differences for prior and subsequent cardiac cycles.

主权项

1. A method of analyzing myocardial instability of a patient, the method comprising:
obtaining values for a physiological parameter representative of myocardial behavior over at least one set of cardiac cycles, wherein each set of cardiac cycles includes at least three cardiac cycles; using a microprocessor to:
determine a reversal point in the physiological parameter in the set of cardiac cycles if:
the value of the physiological parameter during one of the cardiac cycles of the set exceeds the value of the physiological parameter during at least one prior and at least one subsequent cardiac cycles of the set; orthe value of the physiological parameter during one of the cardiac cycles of the set is less than the value of the physiological parameter during at least one prior and at least one subsequent cardiac cycles of the set;identify myocardial instability based on the reversal points in the physiological parameter; andinitiate a treatment of the patient or notify the patient or a healthcare provider of a need for treatment if myocardial instability is identified.