| 发明名称 | Prevention and treatment of pain using antibodies to sphingosine-1-phosphate | ||
| 摘要 | The present invention relates to use of anti-S1P agents, for example, humanized monoclonal antibodies, for prevention and/or treatment of pain, including neuropathic pain, hyperalgesia, allodynia, and chemotherapy-induced pain. | ||
| 申请公布号 | US8871202(B2) | 申请公布日期 | 2014.10.28 |
| 申请号 | US201113246704 | 申请日期 | 2011.09.27 |
| 申请人 | Lpath, Inc. | 发明人 | Sabbadini Roger A. |
| 分类号 | A61K39/395;C07K16/44;A61K39/00 | 主分类号 | A61K39/395 |
| 代理机构 | Acuity Law Group, P.C. | 代理人 | Acuity Law Group, P.C. ;Chambers Daniel M. |
| 主权项 | 1. A method of reducing, or reducing the development of, neuropathic pain, allodynia or hyperalgesia in a human subject, comprising administering to a human subject having or believed to be at risk of having pain an antibody or fragment thereof that binds and neutralizes sphingosine-1-phosphate (S1P), thereby reducing, or reducing the development of, neuropathic pain. | ||
| 地址 | San Diego CA US | ||