发明名称 | Oxoazetidine derivatives, process for the preparation thereof and use thereon in human medicine and in cosmetics | ||
摘要 | Compounds derived from oxoazetidine corresponding to general formula (I); compositions containing same, processes for their preparation and their use in pharmaceutical or cosmetic compositions are described. | ||
申请公布号 | US8871187(B2) | 申请公布日期 | 2014.10.28 |
申请号 | US200913127643 | 申请日期 | 2009.11.04 |
申请人 | Galderma Research & Development | 发明人 | Bouix-Peter Claire;Suzuki Itaru;Rodeville Nicolas;Mauvais Pascale;Pascal Jean-Claude |
分类号 | A61K31/4178;C07D403/12;C07D401/12;A61Q5/10;A61Q17/04;A61Q19/00;A61Q19/04;A61Q19/02;A61K8/49 | 主分类号 | A61K31/4178 |
代理机构 | Dentons US LLP | 代理人 | Dentons US LLP |
主权项 | 1. A compound of formula (I) in which: R1 represents an aryl, a substituted aryl or a cycloalkyl; R2 represents a hydrogen atom, a hydroxyl, a lower alkyl, a substituted lower alkyl, a higher alkyl, a substituted higher alkyl, a cycloalkyl, a cycloalkylalkyl, a lower alkoxy, a substituted lower alkoxy, a higher alkoxy, a substituted higher alkoxy, a cycloalkylalkoxy, or an acyloxy;R3 represents an aralkyl or a substituted aralkyl;R4 represents a heteroaralkyl, a substituted heteroaralkyl, a heteroalkyl or a substituted heteroalkyl; andR5 represents a hydrogen atom, a hydroxyl, an amino, an acylamino or a sulphonamide; or a salt or enantiomer of the compound of formula (I). | ||
地址 | Biot FR |