发明名称 Oxoazetidine derivatives, process for the preparation thereof and use thereon in human medicine and in cosmetics
摘要 Compounds derived from oxoazetidine corresponding to general formula (I); compositions containing same, processes for their preparation and their use in pharmaceutical or cosmetic compositions are described.
申请公布号 US8871187(B2) 申请公布日期 2014.10.28
申请号 US200913127643 申请日期 2009.11.04
申请人 Galderma Research & Development 发明人 Bouix-Peter Claire;Suzuki Itaru;Rodeville Nicolas;Mauvais Pascale;Pascal Jean-Claude
分类号 A61K31/4178;C07D403/12;C07D401/12;A61Q5/10;A61Q17/04;A61Q19/00;A61Q19/04;A61Q19/02;A61K8/49 主分类号 A61K31/4178
代理机构 Dentons US LLP 代理人 Dentons US LLP
主权项 1. A compound of formula (I) in which: R1 represents an aryl, a substituted aryl or a cycloalkyl; R2 represents a hydrogen atom, a hydroxyl, a lower alkyl, a substituted lower alkyl, a higher alkyl, a substituted higher alkyl, a cycloalkyl, a cycloalkylalkyl, a lower alkoxy, a substituted lower alkoxy, a higher alkoxy, a substituted higher alkoxy, a cycloalkylalkoxy, or an acyloxy;R3 represents an aralkyl or a substituted aralkyl;R4 represents a heteroaralkyl, a substituted heteroaralkyl, a heteroalkyl or a substituted heteroalkyl; andR5 represents a hydrogen atom, a hydroxyl, an amino, an acylamino or a sulphonamide; or a salt or enantiomer of the compound of formula (I).
地址 Biot FR