发明名称 Continuous monitor sensor with covalently bound enzyme
摘要 The disclosure concerns a high efficiency electrochemical sensor with high signal yield for determining an analyte in a fluid medium comprising, at least one reference electrode, at least one working electrode having particles of an electrocatalyst in an electrode matrix, and an enzyme that is suitable for determining an analyte is selectively covalently bound to the particles of the electrocatalyst. The disclosure also describes a process for producing the electrochemical sensor and a method for determining an analyte in a fluid medium using the electrochemical sensor. have a high efficiency and thus achieve a high signal yield.
申请公布号 US8871068(B2) 申请公布日期 2014.10.28
申请号 US200812175578 申请日期 2008.07.18
申请人 Roche Diagnostics Operations, Inc. 发明人 Staib Arnulf;Meier Thomas;Mischler Reinhold;Peschel Harald;Hajnsek Martin
分类号 G01N33/487;C12Q1/00;G01N27/327 主分类号 G01N33/487
代理机构 Roche Diagnostics Operations, Inc. 代理人 Roche Diagnostics Operations, Inc.
主权项 1. An electrochemical sensor for determining an analyte in a fluid medium, comprising: at least one reference electrode; at least one working electrode comprising: particles of an electrocatalyst in an electrode matrix, andan enzyme that is suitable for determining an analyte is selectively covalently bound to the particles of the electrocatalyst wherein the enzyme has no covalent bonds with other components of the electrode matrix;wherein the electrode matrix is in a porous form and the electrode matrix additionally contains a conductive electrode material.
地址 Indianapolis IN US