发明名称 |
AN INSULINOTROPIC COMPLEX USING AN IMMUNOGLOBULIN FRAGMENT |
摘要 |
The present invention relates to an insulinotropic peptide conjugate having improved in-vivo duration of efficacy and stability, comprising an insulinotropic peptide, a non-peptide polymer and an immunoglobulin Fc region, which are covalently linked to each other, and a use of the same. The insulinotropic peptide conjugate of the present invention has the in-vivo activity which is maintained relatively high, and has remarkably increased blood half-life, and thus it can be desirably employed in the development of long acting formulations of various peptide drugs. |
申请公布号 |
HK1136504(A1) |
申请公布日期 |
2014.10.24 |
申请号 |
HK20100104054 |
申请日期 |
2010.04.26 |
申请人 |
HANMI SCIENCE CO. LTD. |
发明人 |
SONG, DAE HAE;LIM, CHANG KI;SONG, TAE HUN;KIM, YOUNG HOON;KWON, SE CHANG;LEE, GWAN SUN;JUNG, SUNG YOUB;CHOI, IN YOUNG |
分类号 |
A61K |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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