Raman Imaging Devices and Methods of Molecular Imaging

摘要

In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in one aspect, relate to Raman imaging devices (e.g., Raman endoscope probes) or systems, methods of using Raman agents, Raman imaging devices, and/or systems to image or detect a signal, and the like.

主权项

1. A method of imaging, comprising:
administering at least a first type of Raman agent to a subject, wherein the Raman agent has an affinity for a specific target; introducing a Raman imaging device to an area of the subject;
exposing the area to a light beam from the Raman imaging device, wherein the light beam is scattered by the first type of Raman agent that is associated with the specific target, wherein the light beam that is scattered is referred to as a Raman scattered light energy;detecting the Raman scattered light using the Raman imaging device; and using the Raman scattered light energy to form an image.