发明名称 ISOLATING AND THERAPEUTIC USE OF PERIVASCULAR MEDICINAL CELLS
摘要 Disclosed are perivascular medicinal cells (PVMCs), methods of isolating PVMCs, and a composition comprising PVMCs having medicinal capabilities. Specifically, the disclosure provides a method of isolating PVMCs from an umbilical cord blood vessel or from bone. The disclosure further provides a method of making an enhanced, autologous bone graft, a method of stimulating bone regeneration comprising administering a therapeutically effective amount of bone-derived PVMCs, a method of reconstructing bone tissue, and methods of treating a disease that affects cellular function. PVMCs capable of secreting a site-dependent trophic factor are also described.
申请公布号 US2014314869(A1) 申请公布日期 2014.10.23
申请号 US201214241872 申请日期 2012.08.27
申请人 Caplan Arnold I. 发明人 Caplan Arnold I.
分类号 A61K35/32;B02C19/00 主分类号 A61K35/32
代理机构 代理人
主权项
地址 Cleveland Heights OH US