发明名称 |
Polymorphic and pseudopolymorphic forms of a pharmaceutical compound |
摘要 |
<p>The invention relates to the sodium salt of (1R,2S,5R)-7-oxo-6-sulfooxy-1,6- diazabicyclo[3.2.1]octane-2-carboxamide in hydrated or anhydrous crystallized enantiomeric form and in particular in the novel crystallized polymorphic and pseudopolymorphic forms "A", "B", "D" and "E" defined in the application, as well as the method of preparation. The compound of the invention can be used as a medicament, in particular a beta-lactamase inhibitor.</p> |
申请公布号 |
AU2010304974(B2) |
申请公布日期 |
2014.10.23 |
申请号 |
AU20100304974 |
申请日期 |
2010.10.08 |
申请人 |
ASTRA ZENECA HOLDING FRANCE SAS |
发明人 |
BHATTACHARYA, SISIR;BONNET, ALAIN;DEDHIYA, MAHENDRA G.;DUCANDAS, VERONIQUE;GIULIANI, ALEXANDRE;PRIOUR, ALAIN;RAVAUX, VALERIE;SPARGO, PETER |
分类号 |
C07D471/08;A61K31/4188;A61K31/439;A61K31/551 |
主分类号 |
C07D471/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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