| 发明名称 |
METHOD TO GENERATE DOPAMINERGIC NEURONS FROM MOUSE AND HUMAN CELLS |
| 摘要 |
The present invention relates to a method for reprogramming a differentiated non neuronal cell into a dopaminergic neuron comprising the step of inducing the expression in the differentiated non neuronal cell of at least the protein encoded by the Mash1 human gene or orthologues thereof and the protein encoded by the Nurr1 human gene or orthologues thereof, expression vectors, reprogrammed dopaminergic neuron and uses thereof. |
| 申请公布号 |
US2014315234(A1) |
申请公布日期 |
2014.10.23 |
| 申请号 |
US201113991837 |
申请日期 |
2011.12.13 |
| 申请人 |
Broccoli Vania;Caiazzo Massimiliano |
发明人 |
Broccoli Vania;Caiazzo Massimiliano |
| 分类号 |
C12N5/0793 |
主分类号 |
C12N5/0793 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for reprogramming a differentiated non neuronal cell into a dopaminergic neuron comprising the step of inducing the expression in the differentiated non neuronal cell of at least the protein encoded by the Mash1 human gene or orthologues thereof and the protein encoded by the Nurr1 human gene or orthologues thereof. |
| 地址 |
Milano (MI) IT |
